| dc.description.abstract | 99mTc-DMSA is a common paediatric renal study, where radiopharmaceutical is introduced
intravenously using disposable syringes. Radiopharmaceuticals retain on disposable
syringes, causing under-dosing, impacting on imaging quality. The present study
aimed in specifying the factors a ecting on retention of 99mTc-DMSA in disposable
syringes. A sample of 212 paediatric patients under 15 years of age, underwent the
99mTc-DMSA renal scintigraphy investigation, from 17 th of November 2022 to 28th
of February 2023 were subjected. CAPINTEC radiation dose calibrators were used to
measure the pre and post radiation doses of the used disposable syringes. Six di erent
types of 1 ml/1 cc disposable syringes (Type-1 to 6) and 1 ml insulin syringe (Type-7)
were used. All relevant data pertaining to this study were accumulated. The data were
analysed using Welch’s ANOVA test, Mann-Whitney U test and Spearman’s Rank Order
Correlation statistical tests using SPSS version 26 software with p<0.05 indicating a level of
signi cance. Results indicated a statistically signi cant correlation between retention dose
and radiopharmaceutical dilution. No signi cant di erence in retention with patients’
gender and patient’s positions during the radiopharmaceutical administration. Signi cant
di erences in retention dose among syringe types, injected sites, and radiopharmaceutical
labelling and administering personals were indicated. Syringe Type-1 is less suitable with
its highest retention dose. Type-7 is the best with the lowest retention dose. In conclusion,
the retention of 99mTc-DMSA in disposable syringes is a ected by the radiopharmaceutical
dilution, types of the syringes, injected sites and radiopharmaceutical labelling and
administering personel. Retention is not a ected by pre-dose, patient’s weight, gender,
and patient’s position. | en_US |
