dc.description.abstract | The genus Jeffreycia consists of about 109 species to have medicinal properties. Jeffreycia
zeylanica (Family: Asteraceae) is commonly referred to as “Heen-botiya, Papula or Pupula in
Sinhala and Kappilay or Kuppilay in Tamil”. It is an endemic herbaceous plant in Sri Lanka.
Synonyms of Jeffreycia zeylanica are Cacalia zeylanica Kuntze, Eupatorium zeylanicum L.,
Gymnanthemum zeylanicum (L.), Vernonia zeylanica (L.). This plant can create secondary
metabolites that may have substantial bioactivity. Extracts from leaves, stems and aerial parts are
rich in alkaloids, flavonoids, steroids, triterpenoids, polyphenols, and saponins. These bioactive
compounds lead to various pharmacological properties of Jeffreycia zeylanica. It is utilized in both
Ayurvedic and folk medicine in a variety of methods to treat various illnesses, such as bone
fractures, eczema, asthma, diarrhea, wound, and abscesses also as an anti-venom. Several studies have been carried out on this plant, including the evaluation of anti-inflammatory activity,
antinociceptive activity, antioxidant activity, and anti-tumor activity. The lack of considerable toxicity
associated with the plant Jeffreycia zeylanica makes it a choice for future development of
therapeutic products, with the combination of traditional and novel technologies. A significant
number of presently used antioxidant, anti-inflammatory, anthelminthic, and antitumor agents are
compounds isolated from plants or their synthetic or semisynthetic derivatives. | en_US |