| dc.description.abstract | The significant increase in antimicrobial resistance exhibited by microorganisms
has caused the urgency for novel broad-spectrum antibiotic alternatives. This has
led to extensive research on the therapeutic potential of medicinal plants, its
beneficial effects typically resulting from the presence of plant secondary products.
The current study was sought to detect and determine the effect of the antibacterial
activity of the ethanolic and methanolic extracts of the seeds of fenugreek
(Trigonella foenum-graecum) and the leaves of peppermint (Mentha piperita)
against bacterial strains of Escherichia coli and Staphylococcus aureus. The
antimicrobial susceptibility test, including minimum inhibitory concentration and
minimum bactericidal concentration were determined using the well-diffusion and
broth-dilution methods, respectively. The tested bacterial strains showed a
concentration-dependent growth inhibition towards the plant extracts. The highest
mean growth inhibition zones, being 12.5 ± 1.8 mm and 20.6 ± 2.1 mm, were
obtained with the 100 mg/mL methanolic extracts of both fenugreek and
peppermint, respectively, against S. aureus, with a minimum inhibitory and
minimum bactericidal concentration of 25 mg/mL and 50 mg/mL, respectively, for
the peppermint extract. | en_US |
