dc.contributor.author | Wijayawardhana, NM | |
dc.contributor.author | Cooray, MMDU | |
dc.contributor.author | Uluwaduge, DI | |
dc.contributor.author | Arawwawala, LDAM | |
dc.contributor.author | Jayasuriya, WJABN | |
dc.date.accessioned | 2021-01-05T11:43:05Z | |
dc.date.available | 2021-01-05T11:43:05Z | |
dc.date.issued | 2020 | |
dc.identifier.uri | http://ir.kdu.ac.lk/handle/345/3083 | |
dc.description.abstract | Abstract: Soaps are used as a modality for
topical application of medicinal plants used in
the treatment of skin infections. In herbal
soaps, natural bioactive constituents with a
variety of therapeutic activities are
incorporated into basic soap medium. Natural
herbs are the main ingredients of herbal soap
which are safer and beneficial than the
commercial soaps. Antimicrobial activity of
leaf extracts of Azadirachta indica, Cassia
fistula and flower extract of Nelumbo nucifera
has been evaluated individually and in
combination by a previous study. This study
aims to formulate a novel herbal soap using
the above combined extract and to investigate
its antimicrobial activity. Further, this study
evaluates the physicochemical characteristics
of the soap. The combined extract used in the
formulation of soap was prepared by
incorporating aqueous extracts of A. indica,
N.nucifera and ethanol extract of C.fistula at a
ratio of 4:1:1 according to the previous study.
Soap was formulated by including the
combined extract with other ingredients into
the melted glycerin soap base. The
antimicrobial activity of formulated soap was
tested by agar well diffusion method against
Staphylococcus aureus, Pseudomonas
aeruginosa and Candida albicans and
compared with standard drugs. Test was done
in triplicate. Formulated soap exhibited
antimicrobial activity against tested
organisms with a highest activity against S
aureus. Physiochemical parameters of soap
were evaluated by determining the colour, pH,
% free alkali and % of alcohol insoluble matter
of the soap. pH at 28 ºC was 9.11 and % of
alcohol insoluble matter was 24.6% which
were within the accepted range. Further
studies are pursued to evaluate the safety and
efficacy of the formulated herbal soap. | en_US |
dc.language.iso | en | en_US |
dc.subject | Antimicrobial activity, herbal soap, Azadirachta indica, Cassia fistula, Nelumbo nucifera | en_US |
dc.title | Development of a herbal soap using selected medicinal plants and evaluation of its antimicrobial activity | en_US |
dc.type | Article Full Text | en_US |
dc.identifier.journal | 13th International Research Conference General Sir John Kotelawala Defence University | en_US |
dc.identifier.pgnos | 257-261 | en_US |