https://ir.kdu.ac.lk/handle/345/8504 Wed, 08 Apr 2026 13:41:59 GMT 2026-04-08T13:41:59Z https://ir.kdu.ac.lk/handle/345/8516 The Importance of Cardiopulmonary Exercise Testing (CPET) in Managing Overweight and Associated Comorbidities Wijayasiri, KDCU Sun, 01 Dec 2024 00:00:00 GMT https://ir.kdu.ac.lk/handle/345/8516 2024-12-01T00:00:00Z https://ir.kdu.ac.lk/handle/345/8515 A Case of Recurrent and Seronegative Melioidosis With Deep Seated Abscesses Lamabadusuriya, DA; Perera, TPS; Nakkawita, DMID; Govindapala, DS; Jayasekera, MMPT Melioidosis has a varied clinical presentation. This is a case of recurrent melioidosis diagnosed in a 46 year old male with a prolonged febrile illness and multiple deep seated abscesses. He had intermittent fever since 2020 which was eventually diagnosed as melioidosis in 2021 following isolation of Burkholderia pseudomallei from a blood culture. Treatment was given and he was asymptomatic for seven months, but the fever recurred and needed reinvestigation. Inflammatory markers were high and contrast CT scan revealed multiple abscesses in the liver, spleen and lungs. Bacterial culture in blood and melioidosis antibodies were negative. As other causes were excluded, he was treated as recurrence of melioidosis with a prolonged course of antibiotics and remains well to date. The diagnosis of melioidosis is challenging and clinicians should be aware of the varied presentations. Following diagnosis, treatment with appropriate antibiotics for an adequate duration is vital to ensure complete cure and minimize chances of a recurrence. Sun, 01 Dec 2024 00:00:00 GMT https://ir.kdu.ac.lk/handle/345/8515 2024-12-01T00:00:00Z https://ir.kdu.ac.lk/handle/345/8514 Acute Pancreatitis Following Ingestion of High Dose Garcinia Cambogia Vithana, SMP; Chathuranga, LS; Jayasinghe, S; Don Udayakumara, EA; Wickramasinghe, J; Siriwardana, A; Dissanayake, A Acute pancreatitis is a systemic inflammatory condition carrying significant morbidity and mortality. Garcinia cambogia (GC) has been recently deduced as a rare cause of this condition. A 22-year-old female presented with epigastric pain, nausea and systemic unrest. Her amylase was elevated and had high inflammatory markers. CECT abdomen revealed necrotizing acute pancreatitis. After receiving in-hospital care for two weeks, she made a complete recovery. She had consumed large doses of GC as a weight loss supplement for several months preceding. After excluding other causes of pancreatitis, GC was identified as the possible cause. Acute pancreatitis due to GC is a rare entity with only a handful of cases reported. Large doses of GC are thought to induce oxidative damage in the pancreas causing inflammation. Current evidence for its causal nature is based on history and deduction only. Further research is needed to confirm GC as a cause of pancreatitis. Sun, 01 Dec 2024 00:00:00 GMT https://ir.kdu.ac.lk/handle/345/8514 2024-12-01T00:00:00Z https://ir.kdu.ac.lk/handle/345/8513 Recurrence of a Mature Cystic Teratoma: Masquerading as a Malignant Neoplasm Fernando, R; Nishamalee, KLS We report a case of a mature cystic teratoma (MCT) of the ovary in a 44-year-old woman, characterized by both solid and cystic components derived from all three germ layers: ectoderm, endoderm, and mesoderm. This patient presented with non-specific abdominal discomfort and abdominal bloating for a couple of years. A pelvic ultrasound scan (USS) showed a large complex ovarian tumour with a CA 125 level of 74U/ml. Due to the high calculated Risk of Malignancy Index (RMI), a diagnostic dilemma arose. Consequently, a total abdominal hysterectomy, salpingo oophorectomy, and partial omentectomy were performed, given the suspicion of a malignant ovarian tumour. Macroscopically left ovary was enlarged with a nodular cystic mass. The cut surface showed a multilocular cyst filled with mucoid fluid. Some loculi contained hair and sebaceous material. Microscopically the solid areas of the cyst wall were largely composed of thyroid tissue (10%), the rest of the cyst wall contained mature skin adnexal structures including hair, salivary glands, adipose tissue, bone, lymphoid tissue and smooth muscle. Sun, 01 Dec 2024 00:00:00 GMT https://ir.kdu.ac.lk/handle/345/8513 2024-12-01T00:00:00Z